PGC-1α Mouse Monoclonal Antibody-EnkiLife

PGC-1α Mouse Monoclonal Antibody

规格：20μL 价格：￥600
规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：WB,ELISA
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：PPARGC1A SKU: AMM20461 Category: 鼠单克隆抗体 Tags: -, Mouse, Unconjugated, WB, ELISA, Human

说明书复制

产品概述

产品名称（Product Name）	PGC-1α Mouse Monoclonal Antibody
描述（Description）	Mouse Monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,ELISA
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	PPARGC1A
别名（Alternative Names）	PPARGC1A ;LEM6;PGC1;PGC1A ;PPARGC1 ;Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PGC-1-alpha;PPAR-gamma coactivator 1- alpha ;PPARGC-1-alpha ;Ligand effect modulator 6
基因ID（Gene ID）	10891
蛋白ID（SwissProt ID）	Q9UBK2

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000; ELISA 1:10000;
蛋白分子量（Molecular Weight）	Calculated MW: 91 kDa

研究背景

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008],

研究领域