产品概述
产品性能
免疫原
产品应用
研究背景
Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857).
研究领域
Immunology; Endothelial Cells; Neuroscience; Visual system; Microbiology; SARS Coronavirus; Carbohydrate metabolism; Neurogenesis; Cancer; Metabolism of carbohydrates; Cardiovascular; Endothelial Cell Markers
