Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody

Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ERBB3
SKU: AMRe05900 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

ERBB3

别名(Alternative Names)

ERBB3; HER3; LCCS2; p180 ErbB3; p45 sErbB3; p85 sErbB3;

基因ID(Gene ID)

2065

蛋白ID(SwissProt ID)

P21860

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000

蛋白分子量(Molecular Weight)

148kDa

 

研究背景

Binds and is activated by neuregulins and NTAK. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908).

 

研究领域

ErbB_HER;Calcium;Endocytosis;


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