FYB (3G12) Rabbit Monoclonal Antibody

FYB (3G12) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):FYB1
SKU: AMRe11202 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

FYB (3G12) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

FYB1

别名(Alternative Names)

ADAP; Fyb; FYN binding protein; p120/p130; SLAP130;

基因ID(Gene ID)

2533

蛋白ID(SwissProt ID)

O15117

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,IHC 1:200-1:500,FC 1:50-1:200

蛋白分子量(Molecular Weight)

85kDa

 

研究背景

Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (PubMed:10747096, PubMed:16980616). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 (PubMed:15849195). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity).

 

研究领域

Signal Transduction


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