产品概述
产品性能
免疫原
产品应用
研究背景
Aminopeptidase N (APN, CD13) is a widely expressed, membrane-bound proteolytic enzyme that breaks down peptides during digestion, cleaves cell surface antigens during antigen presentation, and acts as a receptor for human viruses, including several coronaviruses.Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity).
研究领域
Immunology; Cell Type Markers; CD; Myeloid Cells; Stem Cells; Mesenchymal Stem Cells; Surface Molecules; Microbiology; Organism; Virus; RNA Virus; ssRNA positive strand virus; SARS Coronavirus; Hematopoietic Progenitors; Lymphoid; B Lymphocytic Lineage; Myeloid; Dendritic Cell Lineage; Monocytic Lineage
