HIF Prolyl Hydroxylases (11V1) Rabbit Monoclonal Antibody-EnkiLife

HIF Prolyl Hydroxylases (11V1) Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC-P,FC,IP,IF-P
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：P4HTM SKU: AMRe12016 Category: 兔单克隆抗体 Tags: Human, WB, IHC-P, FC, IP, IF-P, Unconjugated, Rabbit, -

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产品概述

产品名称（Product Name）	HIF Prolyl Hydroxylases (11V1) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB,IHC,FC,IP,IF-P
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.
纯化方式（Purification）	Affinity purification

免疫原

基因名（Gene Name）	P4HTM
别名（Alternative Names）	EGLN4 ; HIFPH4; Hypoxia inducible factor prolyl 4 hydroxylase; P4H with transmembrane domain; P4htm; PH4; PHD4; Proline 4 hydroxylase; Prolyl hydroxlase domain containing 4;
基因ID（Gene ID）	54681
蛋白ID（SwissProt ID）	Q9NXG6

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000,IHC 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50,IF-P 1:100-1:200
蛋白分子量（Molecular Weight）	57kDa

研究背景

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

研究领域

Cardiovascular

HIF Prolyl Hydroxylases (11V1) Rabbit Monoclonal Antibody

HIF Prolyl Hydroxylases (11V1) Rabbit Monoclonal Antibody

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