| 产品名称 | 
 Recombinant S. cerevisiae TIM16  | 
| 英文名称 | 
 TIM16  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant S. cerevisiae Mitochondrial Import Inner Membrane Translocase Subunit TIM16 is produced by our E.coli expression system and the target gene encoding Thr54-Ala119 is expressed.  | 
| Accession | 
 P42949  | 
| 表达宿主 | 
 E.coli  | 
| 种属 | 
 S. cerevisiae  | 
| 预测分子量 | 
 7.9 KDa  | 
| 制剂 | 
 Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, pH 8.0.  | 
| 运输方式 | 
 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.  | 
| 复溶 | 
 Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.  | 
| 分子别名 | 
| Mitochondrial import inner membrane translocase subunit TIM16; Presequence translocated-associated motor subunit PAM16; PAM16; TIM16 | 
| 背景介绍 | 
| Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗