| 产品名称 |
Recombinant Mouse APRIL (N-Fc) |
| 英文名称 |
APRIL/TNFSF13/CD256/TALL2 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Tumor Necrosis Factor Ligand Superfamily Member 13 is produced by our Mammalian expression system and the target gene encoding Ala96-Leu240 is expressed with a human IgG1 Fc tag at the N-terminus. |
| Accession |
AAG22534.1 |
| 表达宿主 |
Human Cells |
| 种属 |
Mouse |
| 预测分子量 |
42.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 8% Sucrose, 0.05% Tween 80, pH 6.0. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| A proliferation-inducing ligand; TNFSF13; TALL-2; TRDL-1; CD256 |
| 背景介绍 |
| Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
