| 产品名称 | 
 Recombinant Human TPSB2 (C-6His)  | 
| 英文名称 | 
 Tryptase beta-2/TPSB2  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant Human Tryptase Beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.  | 
| Accession | 
 AAH29356.1  | 
| 表达宿主 | 
 Human Cells  | 
| 种属 | 
 Human  | 
| 预测分子量 | 
 29.64 KDa  | 
| 制剂 | 
 Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.  | 
| 运输方式 | 
 The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.  | 
| 复溶 | 
| 分子别名 | 
| Tryptase Beta-2; Tryptase-2; Tryptase II; TPSB2; TPS2 | 
| 背景介绍 | 
| Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗