| 产品名称 |
Recombinant Human PPC-DC (N-6His) |
| 英文名称 |
PPC-DC/COAC |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Phosphopantothenoylcysteine Decarboxylase is produced by our E.coli expression system and the target gene encoding Met1-Ser204 is expressed with a 6His tag at the N-terminus. |
| Accession |
Q96CD2 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
24.6 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Phosphopantothenoylcysteine Decarboxylase; PPC-DC; PPCDC; COAC |
| 背景介绍 |
| Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and MrsD, all of which use a tightly bound Flavin cofactor to oxidize the Thiol moiety of the substrate to a Thioaldehyde. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
