| 产品名称 |
Recombinant Human NRCAM (C-Fc) |
| 英文名称 |
NRCAM/Neuronal cell adhesion molecule/Nr-CAM/Neuronal surface protein Bravo/hBravo/gCAM-related cell adhesion molecule/Ng-CAM-related/KIAA0343 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Neuronal Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln25-Asn600 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
AAI15737.1 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
91.2 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Neuronal cell adhesion molecule; Nr-CAM; Neuronal surface protein Bravo; hBravo; gCAM-related cell adhesion molecule; Ng-CAM-related; KIAA0343 |
| 背景介绍 |
| Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
