| 产品名称 |
Recombinant Human MMP-9 (C-6His) |
| 英文名称 |
MMP-9/metalloproteinase-9/CLG4B |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Matrix Metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form. |
| Accession |
AAH06093.1 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
77.4 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Hepes,10% Sucrose,150mM NaCl,0.05% Tween 80,2mM CaCl2,pH8.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9 |
| 背景介绍 |
| Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
