| 产品名称 |
Recombinant Human GPNMB (C-6His) |
| 英文名称 |
Osteoactivin/GPNMB |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Glycoprotein Non-Metastatic Melanoma Protein B is produced by our Mammalian expression system and the target gene encoding Lys23-Pro486 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q14956 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
53.09 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Transmembrane Glycoprotein NMB; Transmembrane Glycoprotein HGFIN; GPNMB; HGFIN; NMB |
| 背景介绍 |
| Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
