| 产品名称 |
Recombinant Human DCK (N-6His-T7) |
| 英文名称 |
Deoxycytidine kinase/DCK |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Deoxycytidine Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus. |
| Accession |
P27707 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
34 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, 1mM TCEP, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Deoxycytidine Kinase; dCK; DCK |
| 背景介绍 |
| Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
