| 产品名称 | 
 Recombinant Human AMIGO2 (C-Fc)  | 
| 英文名称 | 
 AMIGO2/Alivin-1/Amphoterin-Induced Protein 2/adhesion molecule with Ig-like domain 2  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant Human Amphoterin-induced Gene And ORF 2 is produced by our Mammalian expression system and the target gene encoding Gly39-His393 is expressed with a human IgG1 Fc tag at the C-terminus.  | 
| Accession | 
 Q86SJ2  | 
| 表达宿主 | 
 Human Cells  | 
| 种属 | 
 Human  | 
| 预测分子量 | 
 67.5 KDa  | 
| 制剂 | 
 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.  | 
| 运输方式 | 
 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.  | 
| 复溶 | 
 Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.  | 
| 分子别名 | 
| Amphoterin-Induced Protein 2; AMIGO-2; Alivin-1; Differentially Expressed in Gastric Adenocarcinomas; DEGA; AMIGO2; ALI1 | 
| 背景介绍 | 
| Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗