SPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody

SPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):SPHK1 SPHK SPK
SKU: APRab06084 Category: 兔多克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

SPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phospho Antibody

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

SPHK1 SPHK SPK

别名(Alternative Names)

Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)

基因ID(Gene ID)

8877

蛋白ID(SwissProt ID)

Q9NYA1

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-2000

蛋白分子量(Molecular Weight)

 

研究背景

catalytic activity:ATP + sphinganine = ADP + sphinganine 1-phosphate.,catalytic activity:ATP + sphingosine = ADP + sphingosine 1-phosphate.,cofactor:Magnesium.,function:Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.,similarity:Contains 1 DAGKc domain.,subunit:Interacts with ACY1 (By similarity). Binds to calmodulin. Interacts with SPHKAP.,tissue specificity:Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.,

 

研究领域


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
  • 在线留言
    关闭