p70 S6 kinase β (phospho Ser423) Rabbit Polyclonal Antibody

p70 S6 kinase β (phospho Ser423) Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ELISA

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):RPS6KB2
SKU: APRab05194 Category: 兔多克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

p70 S6 kinase β (phospho Ser423) Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,ELISA

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phospho Antibody

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

RPS6KB2

别名(Alternative Names)

RPS6KB2; STK14B; Ribosomal protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70

基因ID(Gene ID)

6199

蛋白ID(SwissProt ID)

Q9UBS0

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000, ELISA 1:5000.Not yet tested in other applications.

蛋白分子量(Molecular Weight)

53kDa

 

研究背景

ribosomal protein S6 kinase B2(RPS6KB2) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates specifically ribosomal protein S6.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,

 

研究领域

Insulin Receptor; Regulates Angiogenesis; mTOR; B Cell Receptor; AMPK


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