Cdc42EP4 Rabbit Polyclonal Antibody

Cdc42EP4 Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

种属(Reactivity):Human,Rat,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CDC42EP4
SKU: APRab08521 Category: 兔多克隆抗体 Tags: , , , , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Cdc42EP4 Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

种属反应性(Reactivity)

Human,Rat,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CDC42EP4

别名(Alternative Names)

CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4

基因ID(Gene ID)

23580

蛋白ID(SwissProt ID)

Q9H3Q1

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:20000, IF-P/IF-F/ICC/IF 1:50-200

蛋白分子量(Molecular Weight)

36kDa

 

研究背景

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],function:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with CDC42 and RHOQ, in a GTP-dependent manner.,tissue specificity:Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.,

 

研究领域


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