| 产品名称 |
Recombinant Human CPE (C-6His) |
| 英文名称 |
Carboxypeptidase E/CPE |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Carboxypeptidase E is produced by our Mammalian expression system and the target gene encoding Arg42-Ser453 is expressed with a 6His tag at the C-terminus. |
| Accession |
P16870 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
47.2 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 0.05% Tween80, 250mM Glycine, 2mM EDTA, 50mM L-Arg, pH6.5. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Carboxypeptidase E(CPE for short); Carboxypeptidase H; Enkephalin convertase; Prohormone-processing carboxypeptidase |
| 背景介绍 |
| The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
