Superoxide Dismutase 1 Rabbit Polyclonal Antibody

Superoxide Dismutase 1 Rabbit Polyclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):SOD1
SKU: APRab00451 Category: 兔多克隆抗体 Tags: , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Superoxide Dismutase 1 Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

SOD1

别名(Alternative Names)

SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

基因ID(Gene ID)

6647

蛋白ID(SwissProt ID)

P00441

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 16 kDa; Observed MW: 16 kDa

 

研究背景

SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

 

研究领域

Signal Transduction


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