| 产品名称 |
Recombinant Human NACHRA5 (C-6His) |
| 英文名称 |
NACHRA5/CHRNA5/Neuronal Acetylcholine Receptor Subunit alpha-5 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Neuronal Acetylcholine Receptor Subunit α-5/NACHRA5 is produced by our Mammalian expression system and the target gene encoding Arg23-Thr254 is expressed with a 6His tag at the C-terminus. |
| Accession |
P30532 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
27.6 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Neuronal Acetylcholine Receptor Subunit Alpha-5; CHRNA5; NACHRA5 |
| 背景介绍 |
| Neuronal Acetylcholine Receptor Subunit α-5 (NACHRA5) is a member of the ligand-gated ion channel family. Neuronal AChR is composed of two different type of subunits: α and non-α. When NACHRA5 binds to acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits, leading to the opening of an ion-conducting channel across the plasma membrane. Genetic variations in NACHRA5 have been related to susceptibility to smoking-related behavioral traits and lung cancer, contributing to the smoking quantitative trait locus 3. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
