| 产品名称 | 
 Recombinant Human INPP5A (C-6His)  | 
| 英文名称 | 
 INPP5A/Type I inositol 1,4,5-trisphosphate 5-phosphatase  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant Human Type I Inositol-polyphosphate Phosphatase is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus.  | 
| Accession | 
 Q14642  | 
| 表达宿主 | 
 Human Cells  | 
| 种属 | 
 Human  | 
| 预测分子量 | 
 48.7 KDa  | 
| 制剂 | 
 Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.  | 
| 运输方式 | 
 The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.  | 
| 复溶 | 
| 分子别名 | 
| Type I inositol 1;4;5-trisphosphate 5-phosphatase; INPP5A | 
| 背景介绍 | 
| Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗