| 产品名称 |
Recombinant Human IL-2RB (C-Fc) |
| 英文名称 |
IL-2 R beta/IL-2RB/CD122/IL-2 Receptor Subunit Beta |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Interleukin-2 Receptor Subunit Beta is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
P14784 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
51.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin-2 receptor subunit beta;IL2RB;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;CD122 |
| 背景介绍 |
| Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
