| 产品名称 |
Recombinant Human Galectin 9 (C-6His) |
| 英文名称 |
Galectin-9/LGALS9 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Galectin 9 is produced by our Mammalian expression system and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q3B8N1-2 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
36.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20 mM His-HCl, 8% Trehalose, 2% Mannitol, 0.05% Tween 80, 1mM EDTA, 1 mM DTT, pH6.0. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9 |
| 背景介绍 |
| Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkins disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
