| 产品名称 |
Recombinant Human DPT (C-Fc-6His) |
| 英文名称 |
Dermatopontin/DPT |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Dermatopontin is produced by our Mammalian expression system and the target gene encoding Gln19-Val201 is expressed with a human IgG1 Fc, 6His tag at the C-terminus. |
| Accession |
Q07507 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
49.9 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 4% Sucrose, 4% mannitol, 0.02% Tween80, pH 7.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Dermatopontin; Tyrosine-rich acidic matrix protein; TRAMP and DPT |
| 背景介绍 |
| Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
