| 产品名称 | 
 Recombinant Human CD58 (C-6His)  | 
| 英文名称 | 
 CD58/LFA-3/Lymphocyte function-associated antigen 3  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant Human Lymphocyte Function-associated Antigen 3 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a 6His tag at the C-terminus.  | 
| Accession | 
 AAH05930  | 
| 表达宿主 | 
 Human Cells  | 
| 种属 | 
 Human  | 
| 预测分子量 | 
 22.5 KDa  | 
| 制剂 | 
 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.  | 
| 运输方式 | 
 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.  | 
| 复溶 | 
 Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.  | 
| 分子别名 | 
| Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; CD58; LFA3; Ag3; CD58 antigen | 
| 背景介绍 | 
| Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗