English

Phospho-ROCK2 (Phospho-Tyr722) Rabbit Polyclonal Antibody【50ul/100ul买二送一】

Phospho-ROCK2 (Phospho-Tyr722) Rabbit Polyclonal Antibody【50ul/100ul买二送一】

Cat: APRab06071
★ ★ ★ ★ ★
规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：ROCK2
分类: 兔多克隆抗体 标签: , , , , , ,

说明书 复制

产品概述

产品名称（Product Name）

Phospho-ROCK2 (Phospho-Tyr722) Rabbit Polyclonal Antibody

描述（Description）

Rabbit polyclonal Antibody

宿主（Host）

Rabbit

应用（Application）

WB

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Phosphorylated

同种型（Isotype）

IgG

克隆（Clonality）

Polyclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

ROCK2

别名（Alternative Names）

Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)

基因ID（Gene ID）

9475

蛋白ID（SwissProt ID）

O75116

 

产品应用

稀释比（Dilution Ratio）

WB 1:500-1:2000

蛋白分子量（Molecular Weight）

153kDa

 

研究背景

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by RHOA binding.,function:Protein kinase that phosphorylates a large number of important signaling proteins, and thereby regulates the assembly of the actin cytoskeleton. Promotes formation of stress fibers and of focal adhesion complexes. Plays a role in smooth muscle contraction.,miscellaneous:Inhibited by Y-27632.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 REM (Hr1) repeat.,subcellular location:Cytoplasmic, and associated with actin microfilaments and the plasma membrane.,subunit:Homodimer. Binds RHOA that has been activated by GTP binding. Binds IRS1, RHOB and RHOC.,

 

研究领域

Cell Biology

相关产品


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
    • 在线留言
    关闭
    function uet_report_conversion() { window.uetq = window.uetq || []; window.uetq.push('event', 'wechat_qr_click', { "event_label": "wechat_qr", "event_category": "lead" }); } (function() { var fired = false; function fireWechatConversion() { if (fired) return; fired = true; uet_report_conversion(); } document.addEventListener('click', function(e) { if ( e.target.closest('.rightNav li.howshow') && e.target.closest('.rightNav li.howshow').querySelector('.fa-wechat, .fa-qrcode') ) { fireWechatConversion(); } }); document.addEventListener('mouseover', function(e) { var item = e.target.closest('.rightNav li.howshow'); if (!item) return; if (!item.querySelector('.fa-wechat, .fa-qrcode')) return; var from = e.relatedTarget; if (from && item.contains(from)) return; fireWechatConversion(); }); })();