Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):GSK3A
SKU: APRab00953 Category: 兔多克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

GSK3A

别名(Alternative Names)

Serine/threonine-protein kinase GSK3A

基因ID(Gene ID)

2931

蛋白ID(SwissProt ID)

P49840

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:100-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 51 kDa; Observed MW: 46,51 kDa

 

研究背景

GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

 

研究领域

Neuroscience


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