Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody

Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CHEK2
SKU: APRab03382 Category: 兔多克隆抗体 Tags: , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P,ICC/IF

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CHEK2

别名(Alternative Names)

CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

基因ID(Gene ID)

11200

蛋白ID(SwissProt ID)

O96017

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 61 kDa; Observed MW: 61 kDa

 

研究背景

These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

 

研究领域

Epigenetics and Nuclear Signaling


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