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This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008],function:Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.,polymorphism:The poly-His region of MEOX2 is polymorphic and the number of His varies in the population.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with RNF10.,tissue specificity:Embryo and placenta.,
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