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Phospho-Cdc37 (Ser13) Rabbit Polyclonal Antibody【50ul/100ul买二送一】

Phospho-Cdc37 (Ser13) Rabbit Polyclonal Antibody【50ul/100ul买二送一】

Cat: APRab04426
★ ★ ★ ★ ★
规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC,ICC/IF,ELISA
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：CDC37
分类: 兔多克隆抗体 标签: , , , , , , , , , , ,

说明书 复制

产品概述

产品名称（Product Name）

Phospho-Cdc37 (Ser13) Rabbit Polyclonal Antibody

描述（Description）

Rabbit polyclonal Antibody

宿主（Host）

Rabbit

应用（Application）

WB,IHC,ICC/IF,ELISA

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Phosphorylated

同种型（Isotype）

IgG

克隆（Clonality）

Polyclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

CDC37

别名（Alternative Names）

CDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37

基因ID（Gene ID）

11140

蛋白ID（SwissProt ID）

Q16543

 

产品应用

稀释比（Dilution Ratio）

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

蛋白分子量（Molecular Weight）

44kDa

 

研究背景

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],function:Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.,PTM:Constitutively sumoylated by UBE2I.,similarity:Belongs to the CDC37 family.,subunit:Forms a complex with Hsp90. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.,

 

研究领域

PI3K/Akt

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