CNOT7 Rabbit Polyclonal Antibody

CNOT7 Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CNOT7
SKU: APRab09131 Category: 兔多克隆抗体 Tags: , , , , , , , , , ,

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产品概述

产品名称(Product Name)

CNOT7 Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,ELISA

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CNOT7

别名(Alternative Names)

CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1

基因ID(Gene ID)

29883

蛋白ID(SwissProt ID)

Q9UIV1

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

蛋白分子量(Molecular Weight)

36kDa

 

研究背景

CCR4-NOT transcription complex subunit 7(CNOT7) Homo sapiens The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016],function:Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.,similarity:Belongs to the CAF1 family.,subunit:Interacts with TOB1.,

 

研究领域

RNA degradation;


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