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BST-1 Rabbit Polyclonal Antibody【50ul/100ul买二送一】

BST-1 Rabbit Polyclonal Antibody【50ul/100ul买二送一】

Cat: APRab07674
★ ★ ★ ★ ★
规格：20μL 价格：￥600
规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：WB,ELISA
种属（Reactivity）：Human,Mouse,Rat,Monkey
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：BST1
分类: 兔多克隆抗体 标签: , , , , , , , ,

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产品概述

产品名称（Product Name）

BST-1 Rabbit Polyclonal Antibody

描述（Description）

Rabbit polyclonal Antibody

宿主（Host）

Rabbit

应用（Application）

WB,ELISA

种属反应性（Reactivity）

Human,Mouse,Rat,Monkey

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Unmodified

同种型（Isotype）

IgG

克隆（Clonality）

Polyclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

BST1

别名（Alternative Names）

BST1; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD antigen CD157

基因ID（Gene ID）

683

蛋白ID（SwissProt ID）

Q10588

 

产品应用

稀释比（Dilution Ratio）

WB 1:500-1:2000,ELISA 1:20000-1:40000

蛋白分子量（Molecular Weight）

34kDa

 

研究背景

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008],catalytic activity:NAD(+) + H(2)O = ADP-ribose + nicotinamide.,disease:Rheumatoid arthritis (RA) patients show enhanced expression of BST-1 transcripts in bone marrow stromal cell lines. This suggests that BST-1 overexpression may play a role in B-cell abnormalities in RA.,function:Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.,similarity:Belongs to the ADP-ribosyl cyclase family.,subunit:Homodimer.,tissue specificity:Widely expressed.,

 

研究领域

Nicotinate and nicotinamide metabolism;Calcium;

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