Caveolin-3 (19O1) Rabbit Monoclonal Antibody

Caveolin-3 (19O1) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,IP

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CAV3
SKU: AMRe08023 Category: 兔单克隆抗体 Tags: , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Caveolin-3 (19O1) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CAV3

别名(Alternative Names)

CAV3; M-caveolin; Caveolin 3; VIP21;

基因ID(Gene ID)

859

蛋白ID(SwissProt ID)

P56539

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000,IHC 1:500-1:2000,IP 1:10-1:100

蛋白分子量(Molecular Weight)

17kDa

 

研究背景

Caveolin-3 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564).

 

研究领域

Signal Transduction; Metabolism; Plasma Membrane; Channels; Protein Trafficking; Golgi Proteins; Vitamins / Minerals; Cardiovascular; Heart; Cardiac metabolism; Hypertrophy; Developmental Biolog;y Organogenesis; Skeletal development; Muscle; Neuroscience


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