SIRT2 (1D4) Mouse Monoclonal Antibody

SIRT2 (1D4) Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,ICC/IF

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):SIRT2
SKU: AMM03445 Category: 鼠单克隆抗体 Tags: , , , , , , ,

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产品概述

产品名称(Product Name)

SIRT2 (1D4) Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,ICC/IF

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG2b

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

SIRT2

别名(Alternative Names)

SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2

基因ID(Gene ID)

22933

蛋白ID(SwissProt ID)

Q8IXJ6

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC/IF 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 43 kDa; Observed MW: 43 kDa

 

研究背景

Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.

 

研究领域

Epigenetics and Nuclear Signaling


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