KDM1A (1B2) Mouse Monoclonal Antibody

KDM1A (1B2) Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB

种属(Reactivity):Human,Mouse,Monkey
偶联物(Conjugate):Unconjugated
基因名(Gene Name):KDM1A
SKU: AMM03566 Category: 鼠单克隆抗体 Tags: , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

KDM1A (1B2) Mouse Monoclonal Antibody

描述(Description)

Mouse Monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB

种属反应性(Reactivity)

Human,Mouse,Monkey

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG1

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Ascitic Fluid

 

免疫原

基因名(Gene Name)

KDM1A

别名(Alternative Names)

KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

基因ID(Gene ID)

23028

蛋白ID(SwissProt ID)

O60341

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 93 kDa; Observed MW: 93 kDa

 

研究背景

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

 

研究领域

Epigenetics and Nuclear Signaling


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