Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit Monoclonal Antibody-EnkiLife

Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit Monoclonal Antibody

规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 SKU: AMRe87121 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, Human, Mouse, Rat

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产品概述

产品名称（Product Name）	Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB
种属反应性（Reactivity）	Human,Mouse,Rat

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Phosphorylated
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2
别名（Alternative Names）	AMPK; AMPKa1
基因ID（Gene ID）	5562
蛋白ID（SwissProt ID）	P54646

产品应用

稀释比（Dilution Ratio）	WB 1:1000-1:5000
蛋白分子量（Molecular Weight）	Calculated MW:64,62 kDa; Observed MW:62 kDa

研究背景

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

研究领域