PARP1 Rabbit Polyclonal Antibody

PARP1 Rabbit Polyclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):PARP1
SKU: APRab01384 Category: 兔多克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

PARP1 Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

PARP1

别名(Alternative Names)

PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

基因ID(Gene ID)

142

蛋白ID(SwissProt ID)

P09874

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 113 kDa; Observed MW: 116,24 kDa

 

研究背景

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

 

研究领域

Epigenetics and Nuclear Signaling


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