产品概述
产品性能
免疫原
产品应用
研究背景
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954).
研究领域
Immunology; Innate Immunity; Chemokines; Beta Chemokine Rec. (CCR); Signal Transduction; Signaling Pathway; G Protein Signaling; GPCR; Immune System Diseases; Antiviral Signaling; HIV-related