XRCC4 (7C10) Mouse Monoclonal Antibody

XRCC4 (7C10) Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-F,IHC-P,ICC/IF,IP

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):XRCC4
SKU: AMM03579 Category: 鼠单克隆抗体 Tags: , , , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

XRCC4 (7C10) Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC,ICC/IF,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

XRCC4

别名(Alternative Names)

X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair

基因ID(Gene ID)

7518

蛋白ID(SwissProt ID)

Q13426

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 38 kDa; Observed MW: 38-45 kDa

 

研究背景

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

 

研究领域

Epigenetics and Nuclear Signaling


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