SIRT6 (6C9) Mouse Monoclonal Antibody

SIRT6 (6C9) Mouse Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,ICC/IF,IP

种属(Reactivity):Human,Mouse,Rat,Monkey
偶联物(Conjugate):Unconjugated
基因名(Gene Name):SIRT6
SKU: AMM03651 Category: 鼠单克隆抗体 Tags: , , , , , , , , ,

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产品概述

产品名称(Product Name)

SIRT6 (6C9) Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,ICC/IF,IP

种属反应性(Reactivity)

Human,Mouse,Rat,Monkey

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

SIRT6

别名(Alternative Names)

2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2

基因ID(Gene ID)

51548

蛋白ID(SwissProt ID)

Q8N6T7

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 39 kDa; Observed MW: 42 kDa

 

研究背景

The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.

 

研究领域

Epigenetics and Nuclear Signaling


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