| 产品名称 |
Recombinant Human HMGB1 (C-6His) |
| 英文名称 |
HMGB1/HMG-1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human High Mobility Group Protein B1 is produced by our Mammalian expression system and the target gene encoding Gly2-Glu215 is expressed with a 6His tag at the C-terminus. |
| Accession |
P09429 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
25.8 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
0 |
| 分子别名 |
| High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1 |
| 背景介绍 |
| High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
