| 产品名称 |
Recombinant Human GDF-11 |
| 英文名称 |
GDF-11/BMP-11 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human/Mouse/Rat Growth Differentiation Factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed. |
| Accession |
O95390 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
12.5 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50% glycerol, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
| 复溶 |
0 |
| 分子别名 |
| Growth/differentiation factor 11; GDF-11; Bone morphogenetic protein 11; BMP-11 |
| 背景介绍 |
| Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
