| 产品名称 |
Recombinant Human Afamin (C-6His) |
| 英文名称 |
Afamin/AFM |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus. |
| Accession |
P43652 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
67.6 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Afamin; AFM; ALB2; ALB2alpha-Alb; ALBA; ALBAalpha-albumin; ALF; Alpha-Alb; Alpha-albumin |
| 背景介绍 |
| Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
