English

Pyruvate Dehydrogenase E1 α Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Pyruvate Dehydrogenase E1 α Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Cat: AMRe21508
★ ★ ★ ★ ★
规格：50μL 价格：￥1500
规格：100μL 价格：￥2400
应用（Application）：WB,IHC,IF,IP,ELISA
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：PDHA1
分类: 兔单克隆抗体 标签: , , , , , , , , ,

说明书 复制

产品概述

产品名称（Product Name）

Pyruvate Dehydrogenase E1 α Rabbit Monoclonal Antibody

描述（Description）

Recombinant rabbit monoclonal antibody

宿主（Host）

Rabbit

应用（Application）

WB,IHC,IF,IP,ELISA

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Unmodified

同种型（Isotype）

IgG,Kappa

克隆（Clonality）

Monoclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein

纯化方式（Purification）

Protein A

 

免疫原

基因名（Gene Name）

PDHA1

别名（Alternative Names）

PDHA1;PHE1A;Pyruvate dehydrogenase E1 component subunit alpha;somatic form, mitochondrial;PDHE1-A type I

基因ID（Gene ID）

5160

蛋白ID（SwissProt ID）

P08559

 

产品应用

稀释比（Dilution Ratio）

IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,

蛋白分子量（Molecular Weight）

Calculated MW:43kD;Observed MW:43kD

 

研究背景

Cell localization:Mitochondrion matrix.The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],

 

研究领域

相关产品


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
    • 在线留言
    关闭
    function uet_report_conversion() { window.uetq = window.uetq || []; window.uetq.push('event', 'wechat_qr_click', { "event_label": "wechat_qr", "event_category": "lead" }); } (function() { var fired = false; function fireWechatConversion() { if (fired) return; fired = true; uet_report_conversion(); } document.addEventListener('click', function(e) { if ( e.target.closest('.rightNav li.howshow') && e.target.closest('.rightNav li.howshow').querySelector('.fa-wechat, .fa-qrcode') ) { fireWechatConversion(); } }); document.addEventListener('mouseover', function(e) { var item = e.target.closest('.rightNav li.howshow'); if (!item) return; if (!item.querySelector('.fa-wechat, .fa-qrcode')) return; var from = e.relatedTarget; if (from && item.contains(from)) return; fireWechatConversion(); }); })();