Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody

Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ATF4
SKU: APRab00926 Category: 兔多克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

ATF4

别名(Alternative Names)

Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67

基因ID(Gene ID)

468

蛋白ID(SwissProt ID)

P18848

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 39 kDa; Observed MW: 39 kDa

 

研究背景

ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.

 

研究领域

Epigenetics and Nuclear Signaling


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