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PHAPI2 / APRIL (8K19) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

PHAPI2 / APRIL (8K19) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Cat: AMRe16054
★ ★ ★ ★ ★
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC-P,ICC/IF,FC,IF-P
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：ANP32B
分类: 兔单克隆抗体 标签: , , , , , , , , , ,

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产品概述

产品名称（Product Name）

PHAPI2 / APRIL (8K19) Rabbit Monoclonal Antibody

描述（Description）

Recombinant rabbit monoclonal antibody

宿主（Host）

Rabbit

应用（Application）

WB,IHC,ICC/IF,FC

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Unmodified

同种型（Isotype）

IgG

克隆（Clonality）

Monoclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

ANP32B

别名（Alternative Names）

ANP32B; PAL31; PHAPI2; PHAPI2a; Ssp29;

基因ID（Gene ID）

10541

蛋白ID（SwissProt ID）

Q92688

 

产品应用

稀释比（Dilution Ratio）

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200,FC 1:20-1:50

蛋白分子量（Molecular Weight）

29kDa

 

研究背景

Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription (PubMed:20015864, PubMed:18039846). Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis (PubMed:20015864). Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes (PubMed:20538007, PubMed:18039846). Plays also an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (PubMed:17178712). Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity).

 

研究领域

Cell Biology

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