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NBR1(7C3)Mouse Monoclonal Antibody

NBR1(7C3)Mouse Monoclonal Antibody

Cat: AMM14433
★ ★ ★ ★ ★
规格：20μL 价格：￥600
规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：IF-P,IF-F,ICC/IF,IHC-P
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：NBR1
分类: 鼠单克隆抗体 标签: , , , , , , , , ,

说明书 复制

产品概述

产品名称（Product Name）

NBR1(7C3)Mouse Monoclonal Antibody

描述（Description）

Mouse monoclonal Antibody

宿主（Host）

Mouse

应用（Application）

IHC,ICC/IF

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Unmodified

同种型（Isotype）

IgG

克隆（Clonality）

Monoclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

NBR1

别名（Alternative Names）

Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)

基因ID（Gene ID）

4077

蛋白ID（SwissProt ID）

Q14596

 

产品应用

稀释比（Dilution Ratio）

IHC 1:50-1:300,ICC/IF 1:50-1:200

蛋白分子量（Molecular Weight）

120kDa

 

研究背景

The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],caution:Was originally (PubMed:8069304) thought to be the ovarian carcinoma antigen CA125.,domain:The OPR domain mediates interaction with SQSTM1.,similarity:Contains 1 OPR domain.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ZZ-type zinc finger.,subunit:Homooligomer and heterooligomer. Interacts with SQSTM1, titin/TTN and RNF29.,

 

研究领域

Cell Biology

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