HMGB1 Rabbit Monoclonal Antibody

HMGB1 Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-F,IHC-P,FC

种属(Reactivity):Human, Mouse, Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):HMGB1
SKU: AMRe04024 Category: 兔单克隆抗体 Tags: , , , , , , , , ,

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产品概述

产品名称(Product Name)

HMGB1 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-F,IHC-P,FC

种属反应性(Reactivity)

Human, Mouse, Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

HMGB1

别名(Alternative Names)

HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

基因ID(Gene ID)

3146

蛋白ID(SwissProt ID)

P09429

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100 FC: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW:25 kDa;Observed MW: 29 kDa

 

研究背景

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.

 

研究领域

Epigenetics and Nuclear Signaling


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