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May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies. May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
研究领域